Apparatus and method for all-solid-state fluorescence lifetime imaging
US7508505B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Jul 20, 2006 |
| Grant date | Mar 24, 2009 |
| Priority date | — |
| Expiry date | Mar 27, 2027 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N21/6458
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Fluorescence lifetime imaging microscopy (FLIM) is a powerful technique increasingly used in the life sciences during the past decades. An all-solid-state fluorescence-lifetime-imaging microscope (1) with a simple lock-in imager (4) for fluorescence lifetime detection is described. The lock-in imager (4), originally developed for 3D vision, embeds all the functionalities required for FLIM in a compact system. Its combination with a light-emitting diode (2) yields a cost-effective and user-friendly FLIM unit for wide-field microscopes. The system is suitable for nanosecond lifetime measurements and achieves video-rate imaging capabilities.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.