Combination of polyvinyl acetate with water-insoluble, acid-insoluble, or alkali-insoluble polymers used for the production of film coatings with highly controlled release and high stability

US7510729B2 · kind B2 · utility

Assignee

• BASF SE

Inventors

• Karl Kolter · Ludwigshafen am Rhein, DE
• Roland Bodmeier · Berlin, DE
• Andriy Dashevskiy · Berlin, DE

Key dates

• Filing date: Mar 11, 2003
• Grant date: Mar 31, 2009
• Expiry date: Dec 16, 2024

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K9/5078
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to the combination of polyvinyl acetate and water-insoluble, acid-insoluble, or alkali-insoluble polymers used for producing film coatings for forms of administration in which agents are released in a controlled manner, and methods for the production thereof. The controlled-release properties can be specifically adjusted by means of said combinations, resulting in films having excellent mechanical stability and storage stability. In particular, agents are released independent of the pH by means of the inventive forms of administration.