Method of screening peptides useful in treating traumatic injury to the brain or spinal cord
US7510824B2 · kind B2 · utility
13Cited by
2References
8Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Aug 31, 2004 |
| Grant date | Mar 31, 2009 |
| Priority date | — |
| Expiry date | Jan 20, 2026 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P25/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of screening peptides which bind to at least one PDZ domain and comprise a cell-membrane transduction domain for use in treating traumatic injury to the brain or spinal cord by deforming neurons on a flexible substrate with sublethal stretch, then inflicting a secondary injury, and determining survival of the stretched neurons in the absence or presence of the peptide which is being screened.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.