Patent · US Expired

Method for the combined isolation of magnet-beads from a liquid sample and subsequent thermocyclisation for the polymerase chain reaction (PCR) and associated arrangement

US7510839B2 · kind B2 · utility

0Cited by

0References

16Claims

0Family size

Assignee

Siemens Aktiengesellschaft · DE

Inventors

Walter Gumbrecht · Herzogenaurach, DE
Peter Paulicka · Erlangen, DE
Manfred Stanzel · Erlangen, DE

Key dates

Filing date	Oct 14, 2005
Grant date	Mar 31, 2009
Priority date	—
Expiry date	Oct 14, 2025

Classification

Technology area (CPC G)Physics
CPC primaryG01N35/0098
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

Embodiments generally relate to a PCR wherein a magnetic field is focused in a localized area and also to the possibility of a cyclic transfer of heat. According to at least one embodiment of the invention, a magnetic field gradient is constructed along the direction of flow and the transfer of heat is carried out in a manner perpendicular to the direction of flow. Suitable things are provided therefore. The magnetic field is, in particular, focused by Mumetal® which is arranged on both sides of the flow channel and the temperature is controlled by way of Peltier elements, cooling bodies, and thermal coupling plates.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.