Polynucleotide fragments of an infectious human endogenous retrovirus

US7510862B2 · kind B2 · utility

Assignee

• Avir Green Hills Biotechnology Research Development Trade AG · AT

Inventors

• Klaus Wolff · Mesa, US
• Hubert Pehamberger · Wien, AT
• Andreas Grassauer · Wien, AT
• Thomas Muster · Wien, AT

Key dates

• Filing date: Sep 27, 2002
• Grant date: Mar 31, 2009
• Expiry date: Jun 30, 2024

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2333/15
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Described is a polynucleotide molecule being a fragment of a polynucleotide sequence of an infectious human endogenous retrovirus, said polynucleotide molecule comprising a sequence selected from the group consisting of (a) a sequence with at least 98%, preferably 99%, still preferred 99.5%, identity to a sequence according to SEQ ID No 1, (b) a sequence which hybridises under stringent conditions with a nucleotide sequence according to said SEQ ID No 1, (c) a sequence which differs from said sequences (a) or (b) due to degeneration of the genetic code and (d) a sequence comprising sequences inserted into vectors pCR4-Topo and deposited as “MERV-env”, “MERV-gag”, “MERV-prt” and “MERV-pol” at the DSMZ on 26 Sep. 2001 or fragments thereof.