Chimeric adenoviruses for use in cancer treatment
US7510868B2 · kind B2 · utility
30Cited by
2References
6Claims
0Family size
Inventors
Key dates
| Filing date | May 24, 2005 |
| Grant date | Mar 31, 2009 |
| Priority date | — |
| Expiry date | Apr 21, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2710/10344
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to oncolytic adenoviruses having therapeutic applications. Recombinant chimeric adenoviruses, and methods to produce them are provided. The chimeric adenoviruses of the invention comprise nucleic acid sequences derived from adenoviral serotypes classified within the subgroups B through F and demonstrate an enhanced therapeutic index.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.