Cidofovir peptide conjugates as prodrugs
US7511051B2 · kind B2 · utility
3Cited by
0References
18Claims
0Family size
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Key dates
| Filing date | Jul 1, 2005 |
| Grant date | Mar 31, 2009 |
| Priority date | — |
| Expiry date | Mar 12, 2026 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Cidofovir-based compounds having an amino acid, dipeptide or tripeptide attached to a cidofovir or cyclic cidofovir framework. The compounds show enhanced oral bioavailability and increased binding to the PepT1 transporter. The present invention also provides compositions and methods for treating virus infections, and a method of preparing cidofovir.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.