PRAME peptide analogues
US7511119B2 · kind B2 · utility
6Cited by
18References
26Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 16, 2006 |
| Grant date | Mar 31, 2009 |
| Priority date | — |
| Expiry date | Jun 16, 2026 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/645
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Some embodiments relate to analogs of peptides corresponding to class I MHC-restricted T cell epitopes and methods for their generation. These analogs can contain amino acid substitutions at residues that directly interact with MHC molecules, and can confer improved, modified or useful immunologic properties. Additionally, classes of analogs, in which the various substitutions comprise the non-standard residues norleucine and/or norvaline, are disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.