Enhancement of antibody-cytokine fusion protein mediated immune responses by combined treatment with immunocytokine uptake enhancing agents
US7517526B2 · kind B2 · utility
7Cited by
103References
17Claims
0Family size
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Key dates
| Filing date | Jun 29, 2001 |
| Grant date | Apr 14, 2009 |
| Priority date | — |
| Expiry date | Jun 29, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are methods and compositions for treating tumors. Disclosed methods and compositions enhance the uptake of immunocytokines into tumors, and are based on a combination of an immunocytokine with an immunocytokine uptake enhancing agent. Disclosed methods and compositions are particularly useful for reducing tumor size and metastasis in a mammal.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.