Patent · US Active

Phenylaminopropanol derivatives and methods of their use

US7517899B2 · kind B2 · utility

3Cited by

14References

28Claims

0Family size

Assignee

Wyeth, LLC · US

Inventors

Callain Kim · Collegeville, US
Paige Erin Mahaney · West Orange, US
Eugene J. Trybulski · Princeton Junction, US
Puwen Zhang · Audubon, US
Eugene A. Terefenko · Quakertown, US
Casey Cameron McComas · Phoenixville, US
Michael Anthony Marella · Philadelphia, US
Richard Coghlan · Phoenixville, US
Gavin David Heffernan · Florence, US
Stephen Todd Cohn · Reading, US
An Thien Vu · Pottstown, US
Joseph Peter Sabatucci · Collegeville, US
Fei Ye · Nanuet, US

Key dates

Filing date	Mar 28, 2005
Grant date	Apr 14, 2009
Priority date	—
Expiry date	Aug 15, 2026

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D471/04
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention is directed to phenylaminopropanol derivatives of formula I:or a pharmaceutically acceptable salt thereof, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions ameliorated by monoamine reuptake including, inter alia, vasomotor symptoms (VMS), sexual dysfunction, gastrointestinal and genitourinary disorders, chronic fatigue syndrome, fibromylagia syndrome, nervous system disorders, and combinations thereof, particularly those conditions selected from the group consisting of major depressive disorder, vasomotor symptoms, stress and urge urinary incontinence, fibromyalgia, pain, diabetic neuropathy, and combinations thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.