Patent · US Expired

Optical monitoring of cleaving enzyme activity

US7521188B2 · kind B2 · utility

2Cited by

4References

7Claims

0Family size

Assignee

THE REGENTS OF THE UNIVERSITY OF MICHIGAN · US

Inventors

Hyoungsik Yim · Melrose, US
Mark E. Meyerhoff · Ann Arbor, US
Youngmi Lee · Daejeon, KR

Key dates

Filing date	Mar 2, 2005
Grant date	Apr 21, 2009
Priority date	—
Expiry date	Mar 23, 2026

Classification

Technology area (CPC G)Physics
CPC primaryG01N2333/922
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

A marker molecule for monitoring cleaving enzyme activity is disclosed. The marker molecule includes a protein, a peptide, or an oligonucleotide. A co-factor is conjugated to the protein, the peptide, or the oligonucleotide, thereby forming a co-factor labeled protein, a co-factor labeled peptide, or a co-factor labeled oligonucleotide. The co-factor is adapted to produce an enzymatic signal that is optically detectable.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.