IGF-1 and IGF-2 chimeric polypeptides and therapeutic uses thereof
US7521211B2 · kind B2 · utility
11Cited by
1References
7Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Mar 31, 2006 |
| Grant date | Apr 21, 2009 |
| Priority date | — |
| Expiry date | Nov 11, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A chimeric protein comprising an IGF1 and an IGF2 component and optionally a fusion component (F) and/or a signal sequence, exhibiting improved activity relative to the native IGF1 or IGF2 polypeptide. The fusion component (F) may be a multimerizing component, a targeting ligand, or another active or therapeutic compound.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.