Emissive species for clinical imaging
US7521232B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | May 31, 2006 |
| Grant date | Apr 21, 2009 |
| Priority date | — |
| Expiry date | May 31, 2026 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/582
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to materials and methods useful in the study of cells and species associated with cells. Materials of the present invention may include emissive, photostable organic molecules (e.g., conjugated polymers, conjugated oligomers) that are appropriately functionalized to interact with a cell with essentially no disruption in normal cell functioning. The present invention may be useful in, for example, cell imaging, cell tracking, in vivo monitoring of cellular events, drug delivery, and determination of biological species. In one embodiment, a conjugated polymer or oligomer may be internalized into a cell and may exhibit a strong and stable emissive signal, allowing the cell to be monitored under extensive microscopic conditions for extended periods of time.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.