Patent · US Active

Glucocorticoid receptor ligands for the treatment of metabolic disorders

US7521439B2 · kind B2 · utility

1Cited by

2References

12Claims

0Family size

Assignee

Karo Bio AB · SE

Inventors

Richard D. Bishop · Third Lake, US
Russell D. Cink · Grayslake, US
Bradley D. Gates · Mount Prospect, US
Lars Hagberg · Huddinge, SE
Peer B. Jacobsen · Libertyville, US
Philip R. Kym · Libertyville, US
Chunqiu Lai · Libertyville, US
Marvin R. Leanna · Grayslake, US
James T. Link · Stanford, US
Steven Richards · Brisbane, US
Noah Tu · Gurnee, US
Tom von Geldern · Richmond, US

Key dates

Filing date	Jul 21, 2006
Grant date	Apr 21, 2009
Priority date	—
Expiry date	Mar 24, 2027

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07J1/00
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

This invention relates to novel compounds that are liver selective glucocorticoid receptor antagonists, to methods of preparing such compounds, and to methods for using such compounds in the regulation of metabolism, especially lowering serum glucose levels, insulin levels, or lipid levels, and/or decreasing body weight.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.