Irreversible immobilization of enzymes into polyurethane coatings
US7521504B2 · kind B2 · utility
1Cited by
14References
9Claims
0Family size
Assignee
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Key dates
| Filing date | Dec 19, 2007 |
| Grant date | Apr 21, 2009 |
| Priority date | — |
| Expiry date | Dec 19, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N11/04
- WIPO fieldMacromolecular chemistry, polymers
- WIPO sectorChemistry
Abstract
A method of irreversibly immobilizing an enzyme in a polyurethane and an enzyme-containing polyurethane having a degree of immobilization of the enzyme of approximately 100%. The synthesis of waterborne polyurethanes in the presence of enzyme has enabled the irreversible attachment of the enzyme to the polymeric matrix. The distribution of immobilized enzyme as well as activity retention are homogeneous within the polyurethane. Decreasing ECC hydrophobicity, via the use of a less hydrophobic polyisocyanate prepolymer during polymerization, significantly enhanced the intrinsic activity of the ECC.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.