Tryptase polypeptide and uses thereof

US7521533B2 · kind B2 · utility

Inventors

• John Hunt · Hanstedt, DE
• Hong Wang · Beijing, CN
• Hugh Patrick McNeil · Forbes, AU
• Ahsan Husain · Forbes, AU

Key dates

• Filing date: Feb 28, 2003
• Grant date: Apr 21, 2009
• Expiry date: Jun 22, 2023

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N9/6427
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The present invention provides a purified expressed δ tryptase polypeptide or fragment or analogue thereof, in particular, the human δ tryptase polypeptide or fragment or analogue thereof. The present invention also provides variants of such polypeptides. The invention further relates to methods of diagnosing disease states based on expression of these polypeptides and methods of screening for compounds that interact, bind and/or modulate the activity of the polypeptides.