Inhibiting Smad2/3 signaling promotes neurite outgrowth in dorsal root ganglia
US7524640B2 · kind B2 · utility
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Key dates
| Filing date | Aug 6, 2006 |
| Grant date | Apr 28, 2009 |
| Priority date | — |
| Expiry date | Aug 6, 2026 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P25/28
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Regeneration of a lesioned CNS axon of a mature neuron, determined to be subject to regeneration inhibition by Smad2/3 signaling, is promoted by contacting the neuron with an inhibitor of Smad2/3 signaling sufficient to promote regeneration of the axon.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.