Phospholipid derivatives and process for the production there
US7524981B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Dec 12, 2003 |
| Grant date | Apr 28, 2009 |
| Priority date | — |
| Expiry date | Jul 11, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08G2650/34
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A phospholipid derivative represented by the following formula (1):wherein [PG]k represents a residue of polyglycerin having a polymerization degree of k, wherein k is 2 to 50, R1CO and R2CO independently represent an acyl group having 8 to 22 carbon atoms, symbol “a” independently represents an integer of 0 to 5, symbol “b” independently represents 0 or 1, M represents hydrogen atom, an alkali metal atom, an ammonium, or an organic ammonium, and k1, k2, and k3 represent numbers satisfying the following conditions: 1≦k1≦(k+2)/2, 0≦k2, and k1+k2+k3=k+2. The phospholipid derivative is highly safe for living bodies and can be suitably utilized in drug delivery systems such as liposome, and the like.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.