Use of a preparation based on an antibody directed against a tumor-associated glycosylation

US7527789B2 · kind B2 · utility

Assignee

• Igeneon Krebs-Immuntherapie Forschungs-und Entwicklungs-AG · AT

Inventors

• Hans Loibner · Wien, AT
• Gottfried Himmler · Groß-Enzersdorf, AT
• Thomas Putz · Innsbruck, AT
• Michael Freissmuth · Wien, AT
• Markus Klinger · Wien, AT
• Hesso Farhan · Wien, AT

Key dates

• Filing date: Jun 30, 2003
• Grant date: May 5, 2009
• Expiry date: Jul 23, 2024

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/77
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to the use of a preparation based on an antibody directed against a tumor-associated glycosylation for preparing a medicament for the prophylactic and/or therapeutic treatment for the reduction or inhibition, respectively, of the growth of tumor cells in a cancer patient, as well as to a pharmaceutical preparation containing an antibody directed against a tumor-associated glycosylation. Moreover, the invention relates to a preparation for pharmaceutical and/or diagnostic use, a diagnostic method and an agent for determining the risk of metastasis formation in a cancer patient, as well as a method of producing a preparation based on a body fluid or tissue, in each case using the antibody directed against a tumor-associated glycosylation.