Patent · US Expired

Methods of reducing bone absorption comprising administering an antibody that binds OBM

US7527790B2 · kind B2 · utility

7Cited by
37References
43Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 11, 2002
Grant dateMay 5, 2009
Priority date
Expiry dateMay 20, 2024

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2800/108
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Novel proteins and polypeptides binding to osteoclastogenesis inhibitory factor (OCIF) (OCIF-binding molecules, OBMs) and nucleic acids encoding these proteins and polypeptides are provided. Processes for producing these proteins, polypeptides, and nucleic acid molecules by genetic engineering are provided. Medicinal compounds are provided which comprise proteins and nucleic acids according to the invention, as well as proteins which bind to OBM, including anti-OBM antibodies. These compounds may be used for the treatment of bone disease.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.