Sulfonamides

US7528139B2 · kind B2 · utility

Assignee

• Merck Patent GmbH · DE

Inventors

• Guenter Hoelzemann · Seeheim-Jugenheim, DE
• Helene Crassier · Darmstadt, DE
• Alfred Jonczyk · Darmstadt, DE
• Wolfgang Staehle · Ingelheim am Rhein, DE
• Wilfried Rautenberg · Reinheim, DE

Key dates

• Filing date: Mar 17, 2005
• Grant date: May 5, 2009
• Expiry date: Jun 12, 2025

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of the formula (I), in which R6, R7, R8, R9 and X have the meanings indicated in claim 1, are inhibitors of tyrosine kinases, in particular TIE-2, and Raf kinases and can be employed, inter alia, for the treatment of tumours.