Enhanced inserted yellow fluorescence protein and its application
US7528230B2 · kind B2 · utility
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15Claims
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Key dates
| Filing date | Mar 8, 2003 |
| Grant date | May 5, 2009 |
| Priority date | — |
| Expiry date | Mar 9, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/43595
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Disclosed are mutated genes for green fluorescence proteins and enhanced inserted YFPs expressed therefrom. The mutant proteins not only maintain their fluorescence even at 37° C., but also exhibit about 20 times stronger fluorescence intensities in comparison to the conventional fluorescence proteins. Accordingly, the mutant fluorescence proteins of the present invention can be used as biosensors for detecting and analyzing the bioactivities of desired materials.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.