Process for preparing montelukast and salts thereof
US7528254B2 · kind B2 · utility
2Cited by
2References
29Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 27, 2007 |
| Grant date | May 5, 2009 |
| Priority date | — |
| Expiry date | Feb 27, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D215/18
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides a process for preparing highly pure montelukast and salts thereof by reacting the side-chain precursor 1-(mercaptomethyl)-cyclopropaneacetic acid with 2-(2-(3S)-(3-(7-chloro-2-quinolinyl)-ethenyl)phenyl)-3-(methanesulfonyloxypropyl)phenyl-2-propanol in a solvent mixture containing a base.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.