Methods for modulation of immune responses using humanized immunoglobulins reactive with B7-1 molecules
US7531175B2 · kind B2 · utility
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61Claims
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Key dates
| Filing date | Nov 12, 2004 |
| Grant date | May 12, 2009 |
| Priority date | — |
| Expiry date | Jan 15, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to humanized anti-B7-2 and anti-B7-1 antibodies, wherein each comprise a variable region of non-human origin and at least a portion of an immunoglobulin of human origin. The invention also pertains to methods of treatment for various autoimmune diseases, transplant rejection, inflammatory disorders and infectious diseases by administering humanized anti-B7-2 and/or anti-B7-1 antibodies.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.