Synthesis and characterization of novel systems for guidance and vectorization of molecules of therapeutic interest towards target cells
US7531622B2 · kind B2 · utility
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Key dates
| Filing date | Sep 19, 2003 |
| Grant date | May 12, 2009 |
| Priority date | — |
| Expiry date | Sep 19, 2023 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for preparing a grafted homodetic cyclopeptide forming a framework that defines a grafted upper face and grafted lower face, including synthesizing a linear peptide from modified or unmodified amino acids, some of which carry orthogonal protective groups; intramolecular cyclizing the resulting protected linear peptide; substituting some or all of orthogonal protective groups with a protected precursor; and grafting at least one molecule of interest onto one and/or the other face of the framework via an oxime bond.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.