Monoclonal antibodies that recognize a shared epitope between the human immunodeficiency virus type 1 (HIV-1) capsid (CA/p24) and the human immunodeficiency virus type 2 (HIV-2) capsid (CA/p26)
US7531638B2 · kind B2 · utility
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4Claims
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Key dates
| Filing date | Sep 14, 2004 |
| Grant date | May 12, 2009 |
| Priority date | — |
| Expiry date | Mar 26, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/16222
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to novel monoclonal antibodies which may be used in the detection of Human Immunodeficiency Virus (HIV). These antibodies exhibit an unusually high degree of sensitivity, a remarkably broad range of specificity, and bind to novel shared, non-cross-reactive epitopes. In particular, the monoclonal antibodies of the present invention may be utilized to detect HIV-1 antigen and HIV-2 core antigen in a patient sample.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.