Lipids
US7531676B2 · kind B2 · utility
7Cited by
0References
19Claims
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Assignee
Inventors
Key dates
| Filing date | Jul 26, 2005 |
| Grant date | May 12, 2009 |
| Priority date | — |
| Expiry date | Aug 12, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C271/20
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Bipolar lipids are described which are able to form complexes with polyanions. The lipids comprise a cationic head linked to a hydrophobic backbone and a hydrophilic tail and are capable of self assembly to form stable complexes in aqueous solutions. The lipids are of particular use for the delivery of bioactive substances such as nucleic acids to cells in vitro and especially in vivo.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.