Methods and devices for concentration and purification of analytes for chemical analysis including matrix-assisted laser desorption/ionization(MALDI) mass spectrometry (MS)
US7534338B2 · kind B2 · utility
7Cited by
8References
30Claims
0Family size
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Key dates
| Filing date | Oct 12, 2004 |
| Grant date | May 19, 2009 |
| Priority date | — |
| Expiry date | Oct 12, 2024 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01L2400/0415
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Analytical methods and devices are disclosed for separating low abundance analytes by electrophoretically driving the analytes through a sieving matrix to first remove high molecular weight species. Subsequently the remaining low abundance analytes are electrophoretically focused onto a capture membrane where the analytes become bound within a small capture site. After this step the capture membrane may be allowed to dry and then attached to a conductive MALDI sample plate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.