Detection of nucleic acid sequence differences by comparative genomic hybridization
US7534567B2 · kind B2 · utility
3Cited by
35References
11Claims
0Family size
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Key dates
| Filing date | Feb 16, 2005 |
| Grant date | May 19, 2009 |
| Priority date | — |
| Expiry date | Oct 19, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/156
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides a method of detecting nucleotide sequence differences between two nucleic acid samples. The method employs a comparative genomic hybridization (CGH) technique to analyze the sequence differences between the samples. This method permits the identification of small sequence differences (e.g., sequence divergence of 1% or less) in nucleic acid samples of high complexity (e.g., an entire genome).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.