Certain arylaliphatic and heteroaryl-aliphatic piperazinyl pyrazines and their use in the treatment of serotonin-related diseases

US7534794B2 · kind B2 · utility

Assignee

• Biovitrum AB · SE

Inventors

• Bjorn Nilsson · Foster City, US
• Jan Tejbrant · Stuvsta-Snättringe, SE
• Benjamin Pelcman · Stockholm, SE
• Erik Ringberg · Uppsala, SE
• Markus Thor · Knivsta, SE
• Jonas Nilsson · Lindome, SE
• Mattias Jonsson · Uppsala, SE

Key dates

• Filing date: Oct 11, 2002
• Grant date: May 19, 2009
• Expiry date: Nov 28, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D491/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to compounds of the general formula (I):wherein The compounds may be prepared by per se conventional methods and can be used for treating a human or animal subject suffering from a serotonin-related disorder, such as eating disorders, especially obesity, memory disorders, schizophrenia, mood disorders, anxiety disorders, pain, sexual dysfunctions, and urinary disorders The invention also relates to such use as well as to pharmaceutical compositions comprising a compound of formula (I).