Methods and compositions for the treatment and prevention of staphylococcal infections
US7534857B2 · kind B2 · utility
2Cited by
6References
6Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | May 1, 2006 |
| Grant date | May 19, 2009 |
| Priority date | — |
| Expiry date | May 1, 2026 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K39/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A biologically pure RNAIII inhibiting peptide (RIP), that includes five contiguous amino acids of the sequence YX2PX1TNF, where X1 is C, W, I or a modified amino acid, and X2 is K or S is provided. The RIP further includes amino acids having a sequence that differs from the sequence YX2PX1TNF by two substitutions or deletions, where X1 is C, W, I or a modified amino acid, and X2 is K or S. This agent offers improved protection against and treatment of staphylococcal infections, and related bacteria infections, in mammals.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.