PEGylated soluble gp130-dimers useful as a medicament

US7534862B2 · kind B2 · utility

Assignee

• CONARIS Research Institute AG · DE

Inventors

• Dirk Seegert · Dänischenhagen, DE
• Stefan Schreiber · Edingen-Neckarhausen, DE
• Stefan Rose-John · Kiel, DE
• Georg H. Wätzig · Kiel, DE
• Nikolaus Rahaus · Kiel, DE

Key dates

• Filing date: Jun 23, 2004
• Grant date: May 19, 2009
• Expiry date: Jun 23, 2024

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A polypeptide-dimer comprising two soluble gp130 molecules is described, wherein at least one of said soluble gp130 molecules is covalently linked to polyethylene glycol. Furthermore, a pharmaceutical composition containing said dimer and various medical uses are described.