Human antibodies to human delta like ligand 4
US7534868B1 · kind B1 · utility
28Cited by
2References
6Claims
0Family size
Assignee
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Key dates
| Filing date | Feb 13, 2009 |
| Grant date | May 19, 2009 |
| Priority date | — |
| Expiry date | Feb 13, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/92
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An isolated human antibody or a fragment of a human antibody which specifically binds to human delta-like ligand 4 (hDII4) and blocks hDII4 binding to a Notch receptor. The human anti-hDII4 antibody or antibody fragment binds dimeric hDII4 with an affinity of 75 pM or better, as measured by surface plasmon resonance.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.