Reduction in scattering from a turbid medium by photo-bleaching
US7536213B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 15, 2007 |
| Grant date | May 19, 2009 |
| Priority date | — |
| Expiry date | Jun 15, 2027 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N21/645
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method is proposed whereby photo-bleaching is used not only to change the absorption and fluorescence of a sample but is also employed to change its scattering characteristics. When the compounds which are bleached are contained in regions wherein the real part of the index of refraction is greater than or equal to the average index of the medium, the bleaching will result in reduction in the scattering at wavelengths longer than the wavelength of the bleaching source. This reduction can be useful in measuring the concentration of analytes located at significant depths within turbid media.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.