Enzyme-free isothermal exponential amplification of nucleic acids and nucleic acid analog signals
US7538202B2 · kind B2 · utility
10Cited by
2References
21Claims
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Key dates
| Filing date | Dec 9, 2004 |
| Grant date | May 26, 2009 |
| Priority date | — |
| Expiry date | Dec 9, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6844
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
An enzyme-free, isothermal method of generating an amplification signal indicative of a target nucleic acid molecule is provided, as are compositions for performing such a method. An advantage of the detection system is that it is very sensitive, and can allow for the detection of a single target molecule in a sample.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.