Monoclonal antibody and assay for detecting PIIINP

US7541149B1 · kind B1 · utility

Assignee

• Siemens Healthcare Diagnostics Inc. · US

Inventors

• Elmar Burchardt · Wuppertal, DE
• Werner Kroll · Solingen, DE
• Mathias Gehrmann · Tönisvorst, DE
• Werner Schroder · Wuppertal, DE

Key dates

• Filing date: May 17, 1999
• Grant date: Jun 2, 2009
• Expiry date: May 17, 2019

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K14/78
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The present invention relates to monoclonal antibodies binding to the N-terminal procollagen (III) propeptide (PIIINP) molecule which is a proteolytic fragment emanating from the specific cleavage of procollagen (III) by N-proteinase after exocytosis and to an assay using these antibodies.