Antibodies and related molecules that bind to PSCA proteins
US7541442B2 · kind B2 · utility
21Cited by
4References
19Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 15, 2006 |
| Grant date | Jun 2, 2009 |
| Priority date | — |
| Expiry date | Feb 15, 2026 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Antibodies and molecules derived therefrom that bind to novel PSCA protein, and variants thereof, are described wherein PSCA exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, PSCA provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The PSCA gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with PSCA can be used in active or passive immunization.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.