Oligonucleotides containing molecular rods

US7541448B2 · kind B2 · utility

Assignee

• Roche Diagnostics Operations, Inc. · US

Inventors

• Dieter Heindl · Munich, DE
• Astrid Reiser · Antdorf, DE
• Karim Tabiti · Pocking, DE
• Martina Junius · Bernried, DE
• Alexander Hauber · Wielenbach, DE

Key dates

• Filing date: Dec 2, 2004
• Grant date: Jun 2, 2009
• Expiry date: Nov 16, 2025

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S436/808
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention is directed to an oligonucleotide comprising a molecular rod, wherein preferentially the molecular rod covalently connects the 3′ end of a first nucleotide residue with the 5′ end of a second nucleotide residue. Such oligonucleotides are highly advantageous for real time PCR melting curve analysis.