Tetrahydroisoquinoline derivatives for treating protein trafficking diseases
US7541466B2 · kind B2 · utility
1Cited by
7References
33Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 7, 2004 |
| Grant date | Jun 2, 2009 |
| Priority date | — |
| Expiry date | Jun 25, 2026 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/47
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Tetrahydroisoquinoline derivatives, pharmaceutical compositions comprising them and methods of treating disease are disclosed herein. The disclosed compounds are useful in the treatment and prevention of diseases mediated by chloride channel activity and/or protein trafficking, including, but not limited to, diseases associated with impaired mucociliary clearance such as cystic fibrosis, bronchitis, emphysema, and the like.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.