Process for the preparation of mono- and bis(fluoroalkyl)phosphoranes and the corresponding acids and phosphates

US7541488B2 · kind B2 · utility

Assignee

• Merck Patent GmbH · DE

Inventors

• Nikolai (Mykola) Ignatyev · Duisburg, DE
• Urs Welz-Biermann · Mannheim, DE
• Michael Schmidt · Weiterstadt, DE
• Andriy Kucheryna · Wuppertal, DE
• Helge Willner · Neheim, DE

Key dates

• Filing date: Oct 22, 2004
• Grant date: Jun 2, 2009
• Expiry date: Oct 29, 2025

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07F9/535
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to a method for producing mono(fluoroalkyl)phosphoric acids or bis(fluoroalkyl)phosphoric acids, mono(fluoroalkyl)phosphates or bis(fluoroalkyl)phosphates, and the corresponding phosphoranes thereof. The inventive method comprises at least the step of reacting a bis(fluoroalkyl)phosphonic acid, a (fluoroalkyl)phosphonic acid, or a corresponding derivative of said acids with anhydrous hydrogen fluoride.