Pantoprazole multiparticulate formulations

US7544370B2 · kind B2 · utility

Assignee

• Wyeth, LLC · US

Inventors

• Sripriya Venkata Ramana Rao · Mahwah, US
• Syed M. Shah · Delray Beach, US
• Hanumantharao Tatapudy · Suffern, US
• Richard Saunders · Dobbs Ferry, US
• Mahdi B. Fawzi · Morristown, US
• Arwinder Nagi · Thiells, US
• Shailesh Singh · Powder Springs, US
• Sumon A. Hasan · Rochester, US

Key dates

• Filing date: Sep 30, 2004
• Grant date: Jun 9, 2009
• Expiry date: Feb 7, 2026

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K9/1652
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Pantoprazole sodium multiparticulates are described which avoid sticking to nasogastric and gastronomy tubes. The pantoprazole multiparticulates have a spheroid core of pantoprazole or an enantiomer thereof, or a salt thereof, a surfactant, and a distintegrant; a sub coat which is comprised of hydroxypropyl methylcellulose (hypromellose) and water, an enteric coat on the sub-coat, and a final seal coat over the enteric coat, which is composed of hydroxypropyl methylcellulose (hypromellose) and water.