Modified release dosage forms of skeletal muscle relaxants
US7544372B2 · kind B2 · utility
17Cited by
33References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 6, 2008 |
| Grant date | Jun 9, 2009 |
| Priority date | — |
| Expiry date | Feb 6, 2028 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T29/49826
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A unit dosage form, such as a capsule or the like, for delivering a skeletal muscle relaxant, such as cyclobenzaprine hydrochloride, into the body in an extended or sustained release fashion comprising one or more populations of drug-containing particles (beads, pellets, granules, etc.) is disclosed. At least one bead population exhibits a pre-designed sustained release profile. Such a drug delivery system is designed for once-daily oral administration to maintain an adequate plasma concentration-time profile, thereby providing relief of muscle spasm associated with painful musculoskeletal conditions over a 24 hour period.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.