Identifying cancers sensitive to treatment with inhibitors of notch signaling
US7544476B1 · kind B1 · utility
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9Claims
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Key dates
| Filing date | Jan 27, 2009 |
| Grant date | Jun 9, 2009 |
| Priority date | — |
| Expiry date | Jan 27, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/158
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The disclosure provides a method for identifying cancer tissue sensitive to treatment with an inhibitor of Notch receptor activation. The method comprises determining the level of HeyL gene expression in a sample derived from the cancer tissue, wherein an elevated level of HeyL gene expression alone in the sample indicates sensitivity to the cancer tissue to treatment with an inhibitor of Notch receptor activation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.