Alkynyl pyrrolo[2,3-d]pyrimidines and related analogs as HSP90-inhibitors
US7544672B2 · kind B2 · utility
3Cited by
48References
13Claims
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Key dates
| Filing date | Mar 29, 2006 |
| Grant date | Jun 9, 2009 |
| Priority date | — |
| Expiry date | Jun 9, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Alkynyl pyrrolo[2,3-d]pyrimidines and related analogs are described and demonstrated to have utility as Heat Shock Protein 90 (HSP90) inhibiting agents used in the treatment and prevention of various HSP90 mediated disorders. Methods of synthesis and use of such compounds are also described and claimed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.