Chemical compounds with dual activity, processes for their preparation and pharmaceutical compositions

US7544675B2 · kind B2 · utility

Assignee

• UCB S.A. · BE

Inventors

• Laurent Provins · Soignies, BE
• Berend Jan Van Keulen · Tubize, BE
• John Surtees · Jezus-Eik, BE
• Patrice Talaga · Brussels, BE
• Bernard Christophe · Brussels, BE

Key dates

• Filing date: Mar 29, 2003
• Grant date: Jun 9, 2009
• Expiry date: Jul 24, 2024

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D487/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention concerns chemical compounds combining affinity and antagonism against the human m3 muscarinic receptor with activity as selective phosphodiesterase IV (PDE IV) inhibitors, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.