Piperazinylalkylpyrazole derivatives useful as selective T-type calcium channel blockers and preparation method thereof
US7544686B2 · kind B2 · utility
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9Claims
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Key dates
| Filing date | Aug 25, 2006 |
| Grant date | Jun 9, 2009 |
| Priority date | — |
| Expiry date | Dec 17, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D405/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides for novel piperazinylalkylpyrazole derivatives, the preparation method thereof and the selective T-type calcium channel blocking activity thereof. Particularly, it provides a piperazinylalkylpyrazole derivative as represented by the formula set forth below or its pharmaceutically acceptable salts, and its preparation method thereof.The compound of Formula 1 is a novel piperazinylalkylpyrazole derivative, which particulary has T-type Ca2+ channel blocking effect and thus can be useful as a therapeutic agent for nerve and muscle pain.
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