Process for the preparation of 2-(ethoxymethyl)-tropane derivatives

US7544802B2 · kind B2 · utility

Assignee

• Neurosearch A/S · DK

Inventors

• Richard Ehlenz · Bad Kreuznach, DE
• Oliver Meyer · Ingelheim am Rhein, DE
• Sascha Wagner · Frei-Laubersheim, DE

Key dates

• Filing date: Jan 31, 2005
• Grant date: Jun 9, 2009
• Expiry date: Oct 12, 2025

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P25/28
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to a process for preparing a 2-(ethoxymethyl)-tropane derivative or a pharmaceutically acceptable salt thereof, by reacting the corresponding 2-(hydroxymethyl)-tropane derivative with ethyl bromide in the presence of a base, and a phase transfer catalyst.