Transgenic non-human animals for pharmacological and toxicological studies
US7544854B2 · kind B2 · utility
0Cited by
7References
30Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Apr 18, 2002 |
| Grant date | Jun 9, 2009 |
| Priority date | — |
| Expiry date | Aug 21, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2800/30
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention is directed to the production, breeding and use of transgenic non-human animals such as mice in which specific genes or portions of genes have been replaced by homologues from another animal to make the physiology of the animals so modified more like that of the other animal with respect to drug pharmacokinetics and metabolism. The invention also extends to the use of the genetically modified non-human animals of the invention for pharmacological and/or toxicological studies.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.