Aqueous pharmaceutical compositions of 2,6-diisopropylphenol (propofol) and their uses
US7550155B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 28, 2004 |
| Grant date | Jun 23, 2009 |
| Priority date | — |
| Expiry date | Jan 28, 2024 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P23/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides aqueous pharmaceutical compositions containing a lipophilic therapeutic agent. In particular, the invention provides aqueous pharmaceutical compositions containing the compound 2,6-diisopropylphenol (propofol). Preferred compositions of the invention contain propofol in the presence of at least one block copolymer (for example, P188 or another poloxamer) and a polyethylene glycol (PEG). Compositions of the invention are preferably sterile or are readily sterilized (e.g., by autoclaving) and are suitable for parenteral administration to any animal, including humans. The compositions are also chemically and physically stable over a wide range of environmental conditions and for extended periods of time.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.