Patent · US Active

Substituted aryl cycloalkanoyl derivatives and methods of their use

US7550456B2 · kind B2 · utility

0Cited by

8References

12Claims

0Family size

Assignee

Wyeth, LLC · US

Inventors

Eugene J. Trybulski · Princeton Junction, US
Joseph Peter Sabatucci · Collegeville, US
An Thien Vu · Pottstown, US
Stephen Todd Cohn · Reading, US
Arthur A. Santilli · Havertown, US
Lori Krim Gavrin · Philadelphia, US
Fei Ye · Nanuet, US
Paige Erin Mahaney · West Orange, US

Key dates

Filing date	Feb 14, 2008
Grant date	Jun 23, 2009
Priority date	—
Expiry date	Feb 14, 2028

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D333/58
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The present invention is directed to substituted aryl cycloalkanoyl derivatives, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions ameliorated by monoamine reuptake including, inter alia, vasomotor symptoms (VMS), sexual dysfunction, gastrointestinal and genitourinary disorders, chronic fatigue syndrome, fibromyalgia syndrome, nervous system disorders, and combinations thereof, particularly those conditions selected from the group consisting of major depressive disorder, vasomotor symptoms, stress and urge urinary incontinence, fibromyalgia, pain, diabetic neuropathy, and combinations thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.